Barcelona’s Lionel Messi will miss Wednesday’s Copa del Rey clash against Villanovense at Camp Nou.
Messi returned from injury as a second half substitute against Real Madrid in November and has since played from the start in wins over Roma and Real Sociedad.
However, Enrique has decided to rest the Argentina international against the third division side, following his two-month injury lay-off.
Suarez and Neymar could feature after being included in the 16-man squad.