Costa who picked up his fifth yellow card of the season in a feisty match against Sunderland at the weekend will only observe from the stands as his team mates maintain a high spirit.
As Mourinho’s team get set to host London rivals Tottenham, they look to cement their lead at the top of the table after extending their unbeaten run to 20 matches in all competitions against combative Sunderland.
The blues, who are six points clear on the log, would look to sustain the pace.
History suggests Chelsea should have few problems maintaining or improving on their healthy six-point advantage over second placed Manchester City.
Tottenham have failed to win on any of their previous 27 visits to the Bridge in all competitions – a barren run stretching back to Gary Lineker’s late winner in west London in February 1990.
However, Mauricio Pochettino’s team will make the short trip across the English capital buoyed by their 2-1 win over Everton.
With a series of recent disappointing home results having sparked an angry response from the White Hart Lane faithful, Tottenham could have crumbled when Kevin Mirallas put Everton ahead on Sunday.
However, Christian Eriksen and Roberto Soldado scored to give Spurs a much-needed win – their third in a row in all competitions – and Harry Kane is confident the morale-boosting result, combined with the absence of Costa, gives his side a good chance of finally ending their dismal record at the Bridge.
“We’re coming off three wins in a row now in all competitions, so we’ll take that confidence into the game on Wednesday,” Kane said.
Ahead of the crunchy tie, Jose said; “We don’t cry about injured or suspended players. He is suspended so he can rest and be ready for Newcastle at the weekend,”