The 28-year-old shone in the second half of last season as he inspired Barcelona to the treble, with the club lifting the Champions League, Copa del Rey and La Liga.
Messi finished level on goals with Real Madrid star, Ronaldo and Barcelona team-mate Neymar in Europe in 2014/2015 – as all three men found the back of the net 10 times.
Meanwhile, in the grouping for the UEFA Champions League, Paris Saint Germain will play in Group A along with Real Madrid, Shakhtar Donetsk and Malmo.
Manchester United, who returned to the competition after a season absence, will confront PSV Eindhoven, CSKA Moscow and Wolfsburg in Group B.
Group C has Benfica, Atletico Madrid, Galatasaray and Astana.
In Group D are Juventus, Manchester City, Sevilla and Borussia Monchengladbach.
Defending champions, Barcelona are in Group E with Bayer Leverkusen, A.S. Roma and Bate Borisov.
Bayern Munich, Arsenal, Olympiacos and Dinamo Zagreb are in Group F.
Chelsea, FC Porto, Dynamo Kiev and Maccabi Tel-Aviv make up Group G.
Zenit Saint Petersburg, Valencia, Olympique Lyon and Kaa Gent filled up Group H.