Sunderland manager, David Moyes, has been charged with misconduct after being sent off at Southampton on Wednesday.
The Football Association said it is alleged “Moyes used abusive and/or insulting words towards a match official”.
He has been given until 18:00 BST on Tuesday to respond to the allegation.
The incident took place when Referee Chris Kavanagh waved away appeals for a foul on Sunderland striker Victor Anichebe in the penalty area.
Sunderland lost 1-0 to their hosts as they crashed out of the EFL Cup.
Manchester United also edged past Manchester City with a 1-0 victory while West Ham United beat Chelsea 2 – 1 on Wednesday night.
Arsenal and Liverpool had earlier through to the fifth round as they defeated Reading and Tottenham respectively on Tuesday night.
Former Manchester United Manager, Sir Alex Ferguson, says Liverpool are serious Premier League title contenders this season.
Ferguson said Jurgen Klopp had “revived Liverpool’s enthusiasm” since taking over as manager in October 2015.
“For two decades, Liverpool changed managers without building their own identity.
“You can now sense you truly have to count them in this year,” he told German magazine Kicker.
Liverpool are third in on the league table, sharing points with leaders Manchester City.
In their nine league matches in the present season, they have played four of the current top seven – Arsenal, Tottenham, Chelsea, Manchester United and defending champions, Leicester City.
The Reds have also made it through to the fifth round of the EFL and will face Leeds United in the quarterfinal.
Alex Oxlade-Chamberlain scored two goals as Arsenal booked their spot in the quarter-finals of the EFL Cup with a 2-0 win over Reading.
The Championship side went into the match looking for their first ever win over the Gunners, but it was an easy win for Arsenal in the end, thanks to a double by the Ox, who seemed to be overcoming his difficult start to the season.
The brace takes his tally to five for the season – which is his best return in a season for the Gunners.
Except for Elneny and Iwobi who kept their places, Arsenal fielded a new team, including Lucas Perez, who came off the bench against Boro at the weekend.
Olivier Giroud made his return to the first-team fold as a second half substitute.
Arsenal have not won the League Cup since 1993.
Liverpool are also through to the fifth round courtesy of a brace from another England striker, Daniel Sturridge as they defeated Tottenham 2-1.
The striker opened the scoring early at Anfield after exploiting a Spurs mistake. He doubled the lead in the 60th minute
Liverpool were forced to endure a nervy end to the evening, however, as Vincent Janssen pulled one back for Tottenham with his penalty after Lucas Leiva fouled Erik Lamela in the area.
Manchester City have emerged champions of the League Cup 2016, making it their fourth victory in five finals.
The English football club lifted the League Cup at Wembley after beating Liverpool 3-1 on penalties after the game had finished 1-1 after extra-time.
Fernandinho scored the opener in the 49 minute before Philippe Coutinho created the equaliser in the 83rd minute, before the penalty shootout.
During the penalty, goalkeeper Willy Caballero saved three shots from Lucas Leiva, Philippe Coutinho and Adam Lallana, making them the champion.
Manchester City have won the title in 1970, 1976, 2014 and 2016.