Villarreal stunned Manchester United after a marathon penalty shoot-out, with goalkeeper David de Gea missing the last spot-kick, in the Europa League final to lift their first-ever major trophy on Wednesday in Gdansk.
It finished 1-1 after 120 minutes as Gerard Moreno put the unfancied Spaniards ahead in the 29th minute before Edinson Cavani levelled early in the second half.
But Villarreal won a remarkable shoot-out 11-10, leaving Ole Gunnar Solskjaer still waiting for his first trophy as United manager.
Tottenham cashed in on Anthony Martial’s first-half red card to thrash Manchester United 6-1 as Jose Mourinho enjoyed a dream return to Old Trafford on Sunday.
Son Heung-min and Harry Kane scored twice as Spurs opened up a disorganised United defence at will even before Martial was harshly punished for an off-the-ball clash with Erik Lamela.
Tanguy Ndombele and Serge Aurier were also on target for Tottenham, who showed no ill-effects of a draining week in their fourth match in eight days.
United’s worst home defeat since 2011 will turn the spotlight onto them ahead of the transfer deadline on Monday.
Uruguayan striker Edison Cavani is reportedly set to join the Red Devils, but it is at the other end of the field Ole Gunnar Solskjaer’s men are in desperate need of reinforcements.
Mourinho, who was sacked as United boss in December 2018, has claimed his old club are too often the beneficiaries of dubious penalty decisions. But he could have no complaints when Davinson Sanchez upended Martial inside the area in the first minute.
Bruno Fernandes coolly slotted home the spot-kick to seemingly give the home side the perfect start.
However, within four minutes it was 1-1 as calamitous defending from Eric Bailly, Harry Maguire and Luke Shaw presented Ndombele with the chance to sweep home an equaliser from close range.
Kane was the provider for all four of Son’s goals in a 5-2 win at Southampton two weeks ago and the two combined to perfection once more as Spurs took the lead three minutes later.
Maguire and Aaron Wan-Bissaka were caught ball watching as Kane’s quickly taken free-kick was perfect for the South-Korean to race through and dink the ball over the advancing David De Gea.
The visitors could have had plenty more as a poor touch from Son denied him another one-on-one with De Gea before the Spaniard saved from Aurier.
Any chance of a United revival went with Martial as he was shown a straight red card for raising his hands to Lamela’s face in retaliation to an elbow from the Argentine, which went unpunished from VAR.
Even that decision, though, could not mask a disastrous performance from United, who gifted another goal away within two minutes of losing a man.
Kane intercepted Bailly’s attempt to play out from inside his own box and when the ball broke to Son, he unselfishly squared for Kane to slot into an unguarded net.
Son had been a major injury doubt after suffering a hamstring problem in last weekend’s 1-1 draw with Newcastle, but he was full of energy as he burst into the box to flick his seventh goal of the season between De Gea’s legs.
Solskjaer introduced holding midfielders Scott McTominay and Fred at half-time in a bid to stem the tide, but United were cut open again when Paul Pogba failed to track Aurier’s run and he fired into the far corner from Pierre Emile-Hojbjerg’s perfect pass.
Pogba was at fault again for the sixth as he dived in on Ben Davies and Kane converted emphatically from the penalty spot.
A second straight home defeat to start the season drops United to just above the relegation zone in 16th, while Tottenham move up to fifth.
Anthony Martial’s double and a Mason Greenwood rocket fired Manchester United to a 4-1 win against Newcastle that lifted the mood at Old Trafford after their recent struggles.
Ole Gunnar Solskjaer’s side slumped to an embarrassing 2-0 defeat at lowly Watford last weekend to raise fresh questions about the United manager’s ability to inspire his players.
When Matty Longstaff put Newcastle ahead in the first half on Thursday, Solskjaer’s critics were sharpening their knives again.
But Martial rode to Solskjaer’s rescue with the equaliser and Greenwood’s thunderbolt put United ahead before Marcus Rashford rounded off a first half blitz.
Martial netted again after the interval as United ended a two-match winless run in the Premier League and moved into seventh place, just four points behind fourth placed Chelsea in the race to qualify for the Champions League.
United’s failure to match the levels they showed in their recent win at champions Manchester City during lacklustre efforts against Watford and Everton had put Solskjaer’s future in the spotlight again.
The Norwegian insisted he retains the support of United owners the Glazer family, but he could hardly afford another setback against mid-table opponents like Newcastle.
Scott McTominay tried too hard to set the tone for United when he crunched into a studs-high tackle on Sean Longstaff that earned him the fastest Premier League booking of the season after just 40 seconds.
That was part of a spluttering start from United and Dwight Gayle should have put Newcastle ahead from Joelinton’s pass, but the striker blazed high into the Stretford End.
It was a warning that Solskjaer’s men failed to heed as Newcastle took the lead in the 17th minute.
Matty Longstaff had scored the winner against United on his Premier League debut in October.
The 19-year-old midfielder was making just his third appearance since that dream debut at St James’ Park and this was his first goal since.
Stepping past Luke Shaw, he produced a fine low finish after Joelinton showed impressive composure to tee up Longstaff inside the penalty area.
Now without a clean-sheet in 14 league games, United needed a quick response to lift the gloom and Martial got a helping hand as he delivered the equaliser in the 24th minute.
Andreas Pereira’s neat lay-off from Shaw’s pass gave Martial a sight of goal and French striker’s low shot squirmed under a weak attempted save from Martin Dubravka at his near post.
Newcastle had contributed to their own downfall on that occasion and Greenwood punished more sloppy defending to put United in front in the 36th minute.
Greenwood, making just his third Premier League start, has been one of the few bright spots in a frustrating season.
The 18-year-old showcased his vast potential when he seized on Fabian Schar’s wayward pass and crashed a sublime strike past Dubravka from 20 yards for his eighth goal of the season.
United had all the momentum and increased their lead in the 41st minute, with Rashford climbing highest to power a header into the roof of the net from Aaron Wan-Bissaka’s pin-point cross despite Newcastle appeals for a foul in the build-up.
Following Rashford’s 15th club goal this season, Solskjaer sent on Pogba at half-time for his second appearance since returning from a lengthy ankle injury.
It was Pogba’s compatriot Martial who put the result beyond doubt in the 51st minute.
Sean Longstaff’s woeful attempted back-pass from near the halfway line was intercepted by Martial and he raced into the area before clipping his shot over Dubravka.
Martial was inches away from a hat-trick when his long-range blast hit the post.