The Republican candidates for President traded sharp verbal blows over foreign policy and the future of the Supreme Court in an often unruly and chaotic debate.
After Iowa and New Hampshire, the race has now moved to South Carolina before the February 20 primary.
Front-runner, Donald Trump, repeatedly tangled with Texas Senator Ted Cruz and former Florida Governor, Jeb Bush, in a series of tense exchanges.
The lively audience repeatedly jeered and booed the candidates who were shouting down and interrupting each other.
One of the presidential candidates for 2016 election in the United States (U.S), Donald Trump, has been attacked from all sides in a fiery debate between the top Republican candidates.
The party’s candidate, a billionaire businessman with no political experience, refused to apologise over comments about the wife of Jeb Bush, saying he said nothing wrong.
“No, I won’t do that because I said nothing wrong, but I do hear she’s a lovely woman.”
And he was on the receiving end when Carly Fiorina drew huge applause facing up to his recent jibe over her looks.
Fifteen republicans are vying to be the party’s White House nominee in 2016.
The debate was hosted by CNN.