
Reports say around 40 bodies were counted at the plane wreck site.
The spokesman to the President, Ateny Wek Ateny, told Reuters that there were at least two survivors, a crew member and a child on board.
It is however unclear how many of those were on the plane and how many were on the ground.
Local media reports say the aircraft was a cargo plane heading to Paloch in Upper Nile State and crashed just 800 metres from the runway.
The plane came down on the east bank of the nearby River Nile.